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Biotin and derivatives

Organic heterocyclic compounds and derivatives that consist of a ureido ring and a tetrahydrothiophene ring; ureido contains the radical: NH2CONH−, and tetrahydrothiophene is a five-membered ring consisting of four carbon atoms and a sulfur atom.
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Keyword Search:
301 – 315 of 1,267 results
301

Medchemexpress LLC Azido-PEG8-NHS ester | 1204834-00-3 | 99.5% | 564.58 g/mol | C23H40N4O12 | 50 MG
SDP

Azido-PEG8-NHS ester is an azide-functional PEG8 N-hydroxysuccinimide (NHS) ester used as a cleavable linker and bioconjugation reagent for click chemistry and the synthesis of antibody-drug conjugates and PROTAC linkers. It is supplied as a colorless to light yellow liquid with high purity and is intended for research use.

  • Azide functionality enables copper-catalyzed and strain-promoted click reactions.
  • Peg8 spacer increases hydrophilicity and reduces steric hindrance.
  • NHS ester readily reacts with primary amines for bioconjugation.
  • High reported purity suitable for synthetic and bioconjugation workflows.
  • Storage stability: stable as a pure compound at -20°C for up to 3 years.
  • Solubility: soluble in DMSO (100 mg/mL); ultrasonic agitation may be required.

ENCOMPASS_PREFERRED
302

Medchemexpress LLC Biotin-EDA | 111790-37-5 | 97.5% | 100 MG
SDP

Biotin-EDA is an alkyl chain-based PROTAC linker used in the synthesis of PROTACs, which consist of two different ligands connected by a linker. These PROTACs leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

  • Alkyl chain-based PROTAC linker
  • Used in the synthesis of PROTACs
  • PROTACs leverage the intracellular ubiquitin-proteasome system
  • PROTACs selectively degrade target proteins

ENCOMPASS_PREFERRED
303

Medchemexpress LLC Carbonic acid, bicyclo[2.2.1]hept-5-en-2-yl (2,5-dioxo-1-pyrrolidinyl) ester | 1888335-48-5 | 92.1% | 251.24 g/mol | C12H13NO5 | 10 MG
SDP

Norbornene-NHS is a click-chemistry reagent that functions as a norbornene-derived NHS carbonate dienophile for inverse electron-demand Diels-Alder (IEDDA) conjugation with tetrazines. It is provided for research use to enable efficient amine bioconjugation and labeling applications.

  • Dienophile for inverse electron-demand Diels-Alder (IEDDA) conjugation with tetrazines.
  • NHS carbonate functional group enables efficient coupling to primary amines.
  • Available in small quantities suitable for labeling and bioconjugation experiments.
  • Typical purity about 92.1% and molecular weight 251.24 g/mol.
  • Store sealed and away from moisture; solid at -20°C; in solvent: -80°C for up to 6 months, -20°C for 1 month.
  • Supplied for research use only.

ENCOMPASS_PREFERRED
304

Medchemexpress LLC DBCO-PEG12-NHS ester | 2093934-94-0 | 98.7% | C50H71N3O18 | 50 MG
SDP

DBCO-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is also a click chemistry reagent, containing a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

  • PEG-based PROTAC linker
  • Click chemistry reagent
  • Contains a DBCO group for SPAAC with Azide groups
  • Oil appearance
  • Colorless to light yellow color

ENCOMPASS_PREFERRED
305

Apexbio Technology LLC NHS-SS-11-Biotin(Synonyms: Sulfo-NHS-SS-Biotin, EZ-Link NHS-SS-Biotin, NHS-SS-D-Biotin, N-Hydroxysuccinimidyl-SS-Biotin), 10mg, CAS: 142439-92-7.
SDP

NHS-SS-11-Biotin (CAS 142439-92-7) is an amine-reactive biotinylation reagent commonly used in biochemical research Structurally it possesses an N-hydroxysuccinimide (NHS) ester group that covalently reacts with primary amines of target proteins or biomolecules forming stable amide bonds and releasing sulfo-NHS This reagent features a cleavable disulfide linker and an extended spacer arm of approximately 24 3 enhancing probe accessibility to avidin or streptavidin conjugates It is utilized extensively for reversible biotinylation affinity purification or labeling studies in proteomics and cell biology applications

ENCOMPASS_PREFERRED
306

Apexbio Technology LLC NHS-SS-11-Biotin(Synonyms: Sulfo-NHS-SS-Biotin, EZ-Link NHS-SS-Biotin, NHS-SS-D-Biotin, N-Hydroxysuccinimidyl-SS-Biotin), 25mg, CAS: 142439-92-7.
SDP

NHS-SS-11-Biotin (CAS 142439-92-7) is an amine-reactive biotinylation reagent commonly used in biochemical research Structurally it possesses an N-hydroxysuccinimide (NHS) ester group that covalently reacts with primary amines of target proteins or biomolecules forming stable amide bonds and releasing sulfo-NHS This reagent features a cleavable disulfide linker and an extended spacer arm of approximately 24 3 enhancing probe accessibility to avidin or streptavidin conjugates It is utilized extensively for reversible biotinylation affinity purification or labeling studies in proteomics and cell biology applications

ENCOMPASS_PREFERRED
307

eMolecules​ Mal-Amido-PEG11-amine TFA salt | Broadpharm |809.827 | C33H58F3N3O16 | 98.000 | OC(=O)C(F)(F)F.NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)CCN1C(=O)C=CC1=O | 250mg | 550804710

Mal-Amido-PEG11-amine TFA salt | Broadpharm |809.827 | C33H58F3N3O16 | 98.000 | OC(=O)C(F)(F)F.NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)CCN1C(=O)C=CC1=O | 250mg | 550804710

ENCOMPASS_PREFERRED
308

Medchemexpress LLC IL-15 Human Biotin 50ug | 50ug
SDP

IL-15 protein regulates immune cells stimulates the proliferation of NK cells T cells and B cells and promotes cytokine secretion IL-15 Protein Human (Biotinylated HEK293 Fc-Avi) is the recombinant human-derived IL-15 protein expressed by HEK293 with C-Avi C-hFc labeled tag

ENCOMPASS_PREFERRED
309

Medchemexpress LLC Biotin hydrazide | 66640-86-6 | MFCD00078532 | 98.7% | 258.34 | C10H18N4O2S | 250 MG
SDP

Biotin hydrazide is a carbonyl-reactive biotinylation reagent used to label carbonyl-containing biomolecules such as glycoproteins and glycolipids for detection, enrichment, or affinity-capture applications.

  • Reacts selectively with carbonyl groups to introduce a biotin tag.
  • Suitable for biotinylation of glycoproteins and glycolipids.
  • High purity (98.7%) for consistent experimental results.
  • Soluble in DMSO (6.6 mg/mL) and water (2 mg/mL) with ultrasonic assistance.
  • Chemical formula C10H18N4O2S and molecular weight 258.34 g/mol.
  • Store powder at -20°C for long-term stability; 4°C for shorter-term storage.

ENCOMPASS_PREFERRED
310

Medchemexpress LLC N-Mal-N-bis(PEG2-NHS ester) | 2182601-73-4 | 98.9% | C29H38N4O15 | 50 MG
SDP

N-Mal-N-bis(PEG2-NHS ester) is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs are compounds composed of two different ligands linked together; one ligand binds to an E3 ubiquitin ligase, and the other targets a specific protein. This mechanism exploits the intracellular ubiquitin-proteasome system to selectively degrade target proteins. It is for research use only and not sold to patients.

  • Utilized in the synthesis of PROTACs
  • Exploits intracellular ubiquitin-proteasome system
  • Selectively degrades target proteins
  • For research use only

ENCOMPASS_PREFERRED
311

Medchemexpress LLC Acetic acid, 2-(2-cyclooctyn-1-yloxy)-, 2,5-dioxo-1-pyrrolidinyl ester | 1425803-45-7 | MFCD28898688 | 95.0% | 279.29 g/mol | C14H17NO5 | 50 MG
SDP

Cyclooctyne-O-NHS ester is a cyclooctyne-containing N-hydroxysuccinimide (NHS) ester used as a cleavable ADC linker and click-chemistry reagent for bioconjugation. It undergoes azide-alkyne cycloaddition to enable antibody-drug conjugate construction, labeling, and related conjugation workflows.

  • Cleavable ADC linker for antibody-drug conjugate synthesis.
  • Reacts with azide groups via strain-promoted and copper-catalyzed azide-alkyne cycloaddition.
  • NHS ester chemistry enables efficient conjugation to primary amines.
  • Supplied as a solid in multiple pack sizes suitable for small-scale synthesis.
  • Datasheet and safety data sheet available for handling and storage guidance.

ENCOMPASS_PREFERRED
312

Medchemexpress LLC M-PEG11-acid | 2280998-74-3 | 98.0% | 544.63 g·mol⁻¹ | C24H48O13 | 50 MG
SDP

m-PEG11-acid is a monomethyl polyethylene glycol (11 ethylene glycol units) acid linker used as a reagent for antibody-drug conjugate and PROTAC linker synthesis, and for general bioconjugation.

  • Monomethyl PEG with 11 ethylene glycol units.
  • Molecular weight 544.63 g·mol⁻¹.
  • Purity 98.0%.
  • Cas number 2280998-74-3.
  • Available in small pack sizes, including 50 mg and 100 mg.

ENCOMPASS_PREFERRED
313

Medchemexpress LLC Azido-PEG3-SS-NHS | 436.50 | C15H24N4O7S2 | 10 MG
SDP

Azido-PEG3-SS-NHS is an azide-functionalized, cleavable PEG3 linker used for bioconjugation and antibody-drug conjugate (ADC) synthesis. It contains an NHS ester for amine coupling, a disulfide (SS) cleavage site, and an azide group for click chemistry reactions (CuAAC and SPAAC).

  • Cleavable disulfide linker enabling reductive release
  • Contains NHS ester for efficient amine conjugation
  • Azide group supports CuAAC and strain-promoted click chemistries
  • Liquid form; molecular weight 436.50 and formula C15H24N4O7S2
  • Available in small milligram quantities (e.g., 5 mg, 10 mg)

ENCOMPASS_PREFERRED
314

eMolecules​ 1800414-71-4 | Azido-PEG11-amine | Broadpharm | MFCD08274605 | 570.681 | C24H50N4O11 | 98.000 | NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-] | 1g | 296213760

Azido-PEG11-amine | Broadpharm | 1800414-71-4 | MFCD08274605 | 570.681 | C24H50N4O11 | 98.000 | NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-] | 1g | 296213760

ENCOMPASS_PREFERRED
315

eMolecules​ 58-85-5 | D-Biotin | Ochem Incorporation | MFCD00005541 | 244.310 | C10H16N2O3S | 98.000 | OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 | 5g | 773150949

D-Biotin | Ochem Incorporation | 58-85-5 | MFCD00005541 | 244.310 | C10H16N2O3S | 98.000 | OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 | 5g | 773150949

ENCOMPASS_PREFERRED