Biotin and derivatives
Medchemexpress LLC Bis-PEG6-NHS ester | 1526718-98-8 | 98.0% | 576.55 g/mol | C24H36N2O14 | 50 MG
Bis-PEG6-NHS ester is a PEG-based bifunctional linker bearing two N-hydroxysuccinimide (NHS) ester termini separated by a six-unit polyethylene glycol spacer. It is used to conjugate amine-containing ligands in the synthesis of PROTACs and as a cleavable linker for antibody-drug conjugates (ADCs).
- High purity (98.0%).
- Two NHS ester termini for efficient amine coupling.
- PEG6 spacer provides aqueous solubility and conformational flexibility.
- Suitable as a cleavable linker in ADC construction and for PROTAC linker design.
- Store sealed at -20 °C, away from moisture; unstable in solution, prepare fresh as needed.
Medchemexpress LLC Sulfo-Cy7.5 NHS ester | 2736437-44-6 | 97.0% | 1104.29 g/mol | C49H48K3N3O16S4 | 10 MG
Sulfo-Cy7.5 NHS ester is a water-soluble, hydrophilic near-infrared cyanine dye functionalized as an N-hydroxysuccinimide (NHS) ester for covalent labeling of primary amines on proteins, peptides, and other biomolecules.
- Near-infrared, water-soluble cyanine dye suitable for NIR imaging and fluorescence labeling.
- Reactive NHS ester for efficient covalent coupling to primary amines under mild conditions.
- Reported molecular weight of 1104.29 g/mol for planning conjugation ratios.
- High reported purity suitable for research applications and labeling workflows.
- Available in small milligram pack sizes for pilot studies and labeling optimization.
- Store sealed, away from moisture and light to maintain stability.
Medchemexpress LLC Biotin LC hydrazide | 109276-34-8 | MFCD00077659 | 99.8% | 371.50 g/mol | C16H29N5O3S | 50 MG
Biotin LC hydrazide is a long-chain hydrazide reagent used to introduce a biotin tag onto periodate-oxidized glycans and glycoproteins. It labels aldehyde groups created by mild oxidation, delivering a biotin tag with an extended spacer arm that improves accessibility for detection and capture in downstream assays.
- Reacts with periodate-oxidized glycoproteins and carbohydrate aldehydes.
- Provides an extended spacer arm for improved streptavidin accessibility.
- Suitable for biotinylation of proteins, glycans, and nucleic acids.
- High purity suitable for analytical and preparative applications.
- Provided as a solid in small, research-scale quantities.
Medchemexpress LLC Biotin hydrazide | 66640-86-6 | MFCD00078532 | 98.7% | 258.34 g/mol | C10H18N4O2S | 1 G
Biotin hydrazide is a carbonyl-reactive biotinylation reagent that forms hydrazone linkages with oxidized carbohydrates and other carbonyl groups. It is used to introduce a biotin tag for detection, affinity capture, and enrichment of labeled proteins and glycoconjugates in biochemical assays and proteomics workflows.
- Reacts selectively with aldehydes and ketones after oxidation.
- Enables streptavidin-based detection and affinity purification.
- Suitable for labeling glycoproteins following periodate oxidation.
- Supplied as a solid reagent for solution preparation and storage.
- High purity for reproducible analytical and preparative work.
Apexbio Technology LLC DMG-PEG2000-NHS(Synonyms: DMG-PEG2000-NHS ester, NHS-PEG2000-DMG, DMG PEG NHS ester), 500mg.
DMG-PEG2000-NHS is a polyethylene glycol (PEG) derivative functionalized with an N-hydroxysuccinimide (NHS) ester The reactive NHS ester readily forms stable amide linkages upon interaction with primary amine (-NH ) groups facilitating covalent attachment to peptides proteins or amino-functionalized small molecules Due to these conjugation properties DMG-PEG2000-NHS is commonly employed in biomedical research for constructing drug delivery platforms such as lipid nanoparticles (LNPs) or liposomes particularly for siRNA delivery systems
Sigma Aldrich Fine Chemicals Biosciences Biotin >=99.0% (T) | 58-85-5 | MFCD00005541 | 1G
Biotin >=99.0% (T) | Purity: >=99.0% (T) | Mol Wt: 244.31 | 58-85-5 | MFCD00005541 | 1G
Medchemexpress LLC IL-12 Human Biotin 20ug | 20ug
IL-35 protein plays a key role in immune regulation forming IL-12 cytokine with IL12B or IL-35 cytokine with EBI3/IL27B IL-12 modulates T cell and natural killer cell responses and induces interferon gamma production IL-12 Protein Human (Biotinylated HEK293 His-Avi) is a recombinant protein dimer complex containing human-derived IL-12 protein expressed by HEK293 with C-Avi C-His labeled tag IL-12 Protein Human (Biotinylated HEK293 His-Avi) has molecular weight of 40-45 kDa
Medchemexpress LLC DOTA-NHS-ester (TFA) | 00-00-0 | MFCD23381190 | 95.0% | 615.51 g·mol⁻¹ | C22H32F3N5O12 | 5 MG
DOTA-NHS-ester TFA is an activated N-hydroxysuccinimide (NHS) ester of the DOTA chelator supplied as the trifluoroacetic acid (TFA) salt. It enables efficient conjugation of the DOTA chelator to amine-containing biomolecules for subsequent radiolabeling and imaging applications such as PET and SPECT.
- Activated NHS ester for rapid conjugation to primary amines.
- TFA salt form improves solubility and handling.
- Facilitates stable metal chelation for radiolabeling.
- Suitable for labeling peptides, proteins, and affibodies.
- Available in small-scale research quantities for preclinical work.
Medchemexpress LLC Biotin-lc-lc-nhs | 89889-52-1 | 98.0% | 567.70 | C26H41N5O7S | 25 MG
Biotin-LC-LC-NHS is an N-hydroxysuccinimide (NHS) ester biotinylation reagent with dual long-chain spacers. It covalently attaches biotin to primary amines on proteins, antibodies, and small molecules for labeling, detection, or affinity capture. Handle using appropriate safety precautions and store protected from light at -20°C.
- NHS ester reactive toward primary amines.
- Dual long-chain spacers reduce steric hindrance during labeling.
- Molecular weight 567.70 and formula C26H41N5O7S for precise calculations.
- Purity 98.0% for research-grade applications.
- High solubility in DMSO (100 mg/mL) with recommended freshly opened DMSO.
- Store at -20°C, protect from light, and handle under standard laboratory safety practices.
Medchemexpress LLC L-biotin | 21788-37-4 | 99.7% | 244.31 | C10H16N2O3S | 25 MG
L-biotin is the unnatural enantiomer of biotin and is used as a biochemical research reagent. It is provided as a white to off-white solid with reported high purity and has been observed to bind streptavidin in laboratory assays.
- High purity suitable for research applications.
- White to off-white solid, easy to handle and store.
- Soluble in DMSO at high concentration for in vitro use.
- Available in small solid quantities appropriate for bench-scale experiments.
- Stable when stored frozen as a powder to extend shelf life.